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Structure of 385-01-3
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3-Fluoro-2-nitrophenol features a fluorine atom ortho to a nitro group on a phenolic scaffold, creating a strongly electron-deficient aromatic system. This configuration enhances reactivity in nucleophilic substitution and enables selective functionalization under mild conditions. The compound exhibits bench-stable handling characteristics and integrates readily into synthetic routes targeting bioactive heterocycles and advanced pharmaceutical intermediates.
3-Fluoro-2-nitrophenol serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization of electron-deficient aromatic systems. Its ortho-nitro and fluoro substituents facilitate subsequent coupling reactions, including palladium-catalyzed cross-couplings and nucleophilic aromatic substitutions. The compound exhibits good bench stability and is readily purified by recrystallization, making it suitable for use in the synthesis of heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: