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CS-W001157 4
Total: USD 88.00

4-Chloro-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine

  • CAS No. 384351-45-5

  • Cat. No. CS-0220053
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Chloro-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine|CS-0220053

Structure of 384351-45-5

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General Information

  • CAS No. 384351-45-5
  • Cat. No. CS-0220053
  • Purity ≥95%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₆ClFN₂S
  • Molecular Weight 264.71
  • Synonym(s) OTAVA-BB BB7410330246
  • SMILES C1=C(C=CC(=C1)F)C2=CSC3=NC=NC(=C23)Cl

Synthesis

  • Route1
    • 5-(4-Fluorophenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one|CS-0307738
      35978-37-1
    • ~24%
    • 4-Chloro-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine|CS-0220053
      384351-45-5

    References

    • Zhao, Ailing; Gao, Xin; Wang, Yuanxiang; Ai, Jing; Wang, Ying; Chen, Yi; Geng, Meiyu; Zhang, Ao Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 13 p. 3906 - 3918
  • Route2

    References

    • Golub, Andriy G.; Bdzhola, Volodymyr G.; Briukhovetska, Nadiia V.; Balanda, Anatoliy O.; Kukharenko, Olexander P.; Kotey, Igor M.; Ostrynska, Olga V.; Yarmoluk, Sergiy M. European Journal of Medicinal Chemistry, 2011 , vol. 46, # 3 p. 870 - 876
  • Route3
    • 2-(1-(4-Fluorophenyl)ethylidene)malononitrile|CS-0364220
      579-48-6
    • ~%
    • 4-Chloro-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine|CS-0220053
      384351-45-5

    References

    • Zhao, Ailing; Gao, Xin; Wang, Yuanxiang; Ai, Jing; Wang, Ying; Chen, Yi; Geng, Meiyu; Zhang, Ao Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 13 p. 3906 - 3918

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   4.1508
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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