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Structure of 38274-16-7
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This boronate moiety integrates a trimethylsilyl-protected alkyne for stable, selective coupling in cross-coupling reactions. The ortho-bromophenyl group enables sequential functionalization, while the silyl-protected acetylene offers enhanced stability and moisture tolerance under standard conditions.
(2-Bromophenylethynyl)trimethylsilane serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient access to substituted aryl alkynes. Its trimethylsilyl group enhances stability and facilitates mild deprotection, while the bromoaryl functionality supports robust coupling with diverse nucleophiles. The molecule exhibits excellent bench stability, functional group tolerance, and compatibility with standard reaction conditions, making it ideal for constructing complex scaffolds in medicinal chemistry and materials science workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: