Lot numbers can be found on the outside label of a product:
5-Bromo-3-methylthiophene-2-carboxylic acid
-
CAS No. 38239-45-1
- Cat. No. CS-0153627
- Purity≥97%
- MDL No.MFCD11040352
*For research and further manufacturing use only, not for direct human use.
Structure of 38239-45-1
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 38239-45-1
- Cat. No. CS-0153627
- Purity ≥97%
- MDL No. MFCD11040352
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₅BrO₂S
- Molecular Weight 221.07
- Synonym(s) 5-BROMO-3-METHYLTHIOPHENE-3-CARBOXYLIC ACID
- SMILES CC1=C(C(=O)O)SC(=C1)Br
Description
5-Bromo-3-methylthiophene-2-carboxylic acid features a brominated thiophene core with a methyl group at the 3-position and a carboxylic acid at the 2-position, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient bromo substituent facilitates cross-coupling reactions, while the carboxylic acid group provides a versatile handle for amide formation or metal chelation. This structure offers enhanced solubility in organic media and stability under standard bench conditions, supporting efficient use in medicinal chemistry and materials synthesis workflows.
Application
5-Bromo-3-methylthiophene-2-carboxylic acid serves as a versatile building block for the synthesis of substituted thiophenes and heterocyclic scaffolds. Its bromo and carboxylic acid functionalities enable direct coupling reactions, including Suzuki-Miyaura and Stille couplings, and facilitate derivatization via amide or ester formation. The molecule exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science.
Synthesis
-
Route1
-
In-stock
14282-78-1 - ~80%
-
In-stock
38239-45-1
References
-
AGOURON PHARMACEUTICALS, INC. Patent: US2004/266796 A1, 2004 ; Location in patent: Page 13 ;
-
-
Route2
-
In-stock
23806-24-8 - ~37%
-
In-stock
38239-45-1
References
-
NOVARTIS AG; XENON PHARMACEUTICALS INC. Patent: WO2008/74835 A1, 2008 ; Location in patent: Page/Page column 78 ; WO 2008/074835 A1
-
-
Route3
-
38239-46-2 - ~%
-
In-stock
38239-45-1
References
-
FibroGen, Inc. Patent: US2006/199836 A1, 2006 ; Location in patent: Page/Page column 22 ; US 20060199836 A1
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 37.3
- LogP 2.51722
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 38239-45-1 sigma38239-45-1 manufacturer38239-45-1 price38239-45-1 structure38239-45-1 SDSbuy 38239-45-138239-45-1 supplier38239-45-1 uses38239-45-1 molecular weightprice of 38239-45-138239-45-1 chemical name formula of 38239-45-1