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Structure of 38116-61-9
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2-Hydroxy-6-methylnicotinic acid features a strategically positioned hydroxyl group and methyl substituent on the pyridine ring, enhancing its solubility and reactivity in synthetic transformations. This configuration supports efficient coupling reactions and serves as a key scaffold in bioactive molecule design.
2-Hydroxy-6-methylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted nicotinamide derivatives and heterocyclic scaffolds. Its ortho-hydroxyl and methyl groups provide defined regiochemistry for downstream functionalization, including esterification, amidation, and metal-catalyzed coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: