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Structure of 380430-61-5
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N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide features a boronate ester group conjugated to an aryl amide scaffold, enabling efficient Suzuki-Miyaura coupling under mild conditions. The tetramethyl-substituted dioxaborolane moiety imparts enhanced stability and moisture tolerance, while the acetamide linkage provides favorable solubility and compatibility in aqueous-organic reaction media. This reagent integrates seamlessly into complex molecular architectures during synthetic workflows.
N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide serves as a versatile boronate building block for Suzuki-Miyaura coupling reactions. Its ortho-substituted arylboronate functionality enables efficient C–C bond formation under mild conditions, with excellent stability and ease of purification. The acetamide group provides moderate polarity and functional group tolerance, facilitating downstream transformations in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: