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CS-W001157 4
Total: USD 88.00

2-(Pyridin-2-yl)propan-2-ol

  • CAS No. 37988-38-8

  • Cat. No. CS-W021455
  • Purity≥98%
  • MDL No.MFCD00209259

*For research and further manufacturing use only, not for direct human use.

2-(Pyridin-2-yl)propan-2-ol|CS-W021455

Structure of 37988-38-8

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General Information

  • CAS No. 37988-38-8
  • Cat. No. CS-W021455
  • Purity ≥98%
  • MDL No. MFCD00209259
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight 137.18
  • Synonym(s) a,a-DiMethyl-2-PyridineMethanol
  • SMILES CC(C)(O)C1=NC=CC=C1

Description

2-(Pyridin-2-yl)propan-2-ol features a sterically hindered tertiary alcohol anchored to a pyridine ring, delivering enhanced stability and predictable reactivity. This bench-stable scaffold integrates readily into synthetic sequences requiring polar, nitrogen-containing building blocks.

Application

2-(Pyridin-2-yl)propan-2-ol serves as a versatile building block in synthetic organic chemistry, offering a sterically hindered tertiary alcohol appended to a pyridine ring. Its stability under ambient conditions and compatibility with common functional groups enable reliable use in nucleophilic substitution, metal-catalyzed coupling, and heterocycle elaboration. The molecule functions as a scaffold for bioactive compound synthesis and facilitates the construction of complex architectures through controlled deprotonation or oxidation.

Synthesis

  • Route1
    • null|null
      109-04-6
    • null|null
      67-64-1
    • ~30%
    • In-stock
      2-(Pyridin-2-yl)propan-2-ol|CS-W021455
      37988-38-8

    References

    • Trecourt, Francois; Breton, Gilles; Bonnet, Veronique; Mongin, Florence; Marsais, Francis; Queguiner, Guy Tetrahedron, 2000 , vol. 56, # 10 p. 1349 - 1360
  • Route2
    • null|null
      110-86-1
    • null|null
      67-64-1
    • ~36%
    • In-stock
      2-(Pyridin-2-yl)propan-2-ol|CS-W021455
      37988-38-8

    References

    • Gros, Philippe; Fort, Yves; Caubere, Paul Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 24 p. 3597 - 3600
  • Route3
    • 1-(Pyridin-2-yl)ethanone  Imatinib Impurity|CS-0167014
      1122-62-9
    • null|null
      917-64-6
    • ~60%
    • In-stock
      2-(Pyridin-2-yl)propan-2-ol|CS-W021455
      37988-38-8

    References

    • Wong; Yang; Zhou; Lee; Mak; Ng New Journal of Chemistry, 2001 , vol. 25, # 2 p. 353 - 357

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.309
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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