Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

Name: Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 379270-35-6
Cat. No. CS-W004381
Purity≥97%
MDL No.MFCD28386144

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate|CS-W004381

Structure of 379270-35-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 379270-35-6
Cat. No. CS-W004381
Purity ≥97%
MDL No. MFCD28386144
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₁₈N₅O₄P
Molecular Weight 363.31
Synonym(s) None
SMILES C[C@@H](OCP(OC1=CC=CC=C1)(O)=O)CN2C=NC3=C(N)N=CN=C23

Description

This phenyl hydrogen phosphonate derivative integrates a purine nucleobase with a chiral propanol linker, enabling site-specific conjugation in nucleoside analog synthesis. The pendant amino group supports further functionalization, while the phosphonate moiety enhances metabolic stability and cell permeability for applications in antiviral and anticancer research.

Application

Phenyl hydrogen (((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate serves as a key building block for nucleoside analog synthesis, enabling efficient phosphorylation at the 5′-position. Its chiral propanediol linker provides stereocontrol in glycosylation reactions, while the purine amine group allows direct functionalization for antiviral and anticancer scaffold development. The phosphonate moiety offers enhanced metabolic stability and facilitates coupling under standard Mitsunobu or amide bond-forming conditions.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 125.38
LogP 2.0355
H_Acceptors 8
H_Donors 2
Rotatable_Bonds 7

Other Classifications

Building Blocks Functional Group Phosphate

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

379270-35-6 sigma379270-35-6 manufacturer379270-35-6 price379270-35-6 structure379270-35-6 SDSbuy 379270-35-6379270-35-6 supplier379270-35-6 uses379270-35-6 molecular weightprice of 379270-35-6379270-35-6 chemical name formula of 379270-35-6

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

CAS No. 379270-35-6

Recommended Products