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Structure of 37777-71-2
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4-Chloro-2-nitrophenylacetic acid features a chlorinated aromatic ring paired with electron-withdrawing nitro and carboxylic acid functionalities, enabling direct integration into conjugate addition and coupling reactions. This bench-stable scaffold supports efficient derivatization in synthetic medicinal chemistry workflows.
4-Chloro-2-nitrophenylacetic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles and pharmaceutical intermediates. Its ortho-nitro and para-chloro substituents provide complementary reactivity for nucleophilic substitution, palladium-catalyzed coupling, and cyclization reactions. The carboxylic acid functionality facilitates direct derivatization or salt formation, enhancing solubility and purification. Bench-stable and compatible with standard synthetic workflows, it functions reliably in the construction of complex scaffolds used in drug discovery pipelines.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: