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CS-W001157 4
Total: USD 88.00

(E)-Ethyl 4-bromobut-2-enoate

  • CAS No. 37746-78-4

  • Cat. No. CS-W007837
  • Purity≥90%
  • MDL No.MFCD00000247

*For research and further manufacturing use only, not for direct human use.

(E)-Ethyl 4-bromobut-2-enoate|CS-W007837

Structure of 37746-78-4

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General Information

  • CAS No. 37746-78-4
  • Cat. No. CS-W007837
  • Purity ≥90%
  • MDL No. MFCD00000247
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉BrO₂
  • Molecular Weight 193.04
  • Synonym(s) Ethyl 4-bromocrotonate
  • SMILES O=C(OCC)/C=C/CBr

Description

(E)-Ethyl 4-bromobut-2-enoate features a conjugated enoate system with a terminal vinyl bromide, enabling efficient cross-coupling and Michael addition reactions. This bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring electrophilic alkenyl halides.

Synthesis

  • Route1
    • Ethyl (e)-4-hydroxybut-2-enoate|CS-0683674
      10080-68-9
    • ~84%
    • In-stock
      (E)-Ethyl 4-bromobut-2-enoate|CS-W007837
      37746-78-4

    References

    • KOLON LIFE SCIENCE, INC. Patent: US2012/46494 A1, 2012 ; Location in patent: Page/Page column 5 ;
  • Route2
    • null|null
      623-70-1
    • ~77%
    • In-stock
      (E)-Ethyl 4-bromobut-2-enoate|CS-W007837
      37746-78-4

    References

    • Toutchkine; Aebisher; Clennan Journal of the American Chemical Society, 2001 , vol. 123, # 21 p. 4966 - 4973
  • Route3
    • Ethyl 2-hydroxybut-3-enoate|CS-0243293
      91890-87-8
    • ~%
    • In-stock
      (E)-Ethyl 4-bromobut-2-enoate|CS-W007837
      37746-78-4

    References

    • Glattfeld; Lee Journal of the American Chemical Society, vol. 62, p. 355

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.5006
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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