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CS-W001157 4
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1'-Benzyl-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one

  • CAS No. 37663-42-6

  • Cat. No. CS-0060532
  • Molecule weight293.36
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1'-Benzyl-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one|CS-0060532

Structure of 37663-42-6

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General Information

  • CAS No. 37663-42-6
  • Cat. No. CS-0060532
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₉NO₂
  • Molecular Weight 293.36
  • Synonym(s) 1'-(phenylmethyl)-spiro[isobenzofuran-1(3H),4'-piperidin]-3-one
  • SMILES C1=CC=C(C=C1)CN2CCC3(CC2)C4=CC=CC=C4C(=O)O3

Synthesis

  • Route1
    • null|null
      3612-20-2
    • In-stock
      Methyl 2-iodobenzoate|CS-W007334
      610-97-9
    • ~68%
    • null|null
      93-58-3
    • 1'-Benzyl-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one|CS-0060532
      37663-42-6

    References

    • Kuethe, Jeffrey T.; Maloney, Kevin M. Tetrahedron, 2013 , vol. 69, # 25 p. 5248 - 5258
  • Route2

    References

    • Ogino, Yoshio; Ohtake, Norikazu; Nagae, Yoshikazu; Matsuda, Kenji; Moriya, Minoru; Suga, Takuya; Ishikawa, Makoto; Kanesaka, Maki; Mitobe, Yuko; Ito, Junko; Kanno, Tetsuya; Ishihara, Akane; Iwaasa, Hisashi; Ohe, Tomoyuki; Kanatani, Akio; Fukami, Takehiro Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 18 p. 5010 - 5014
  • Route3

    References

    • Trapella, Claudio; Fischetti, Carmela; Pela', Michela; Lazzari, Ilaria; Guerrini, Remo; Calo', Girolamo; Rizzi, Anna; Camarda, Valeria; Lambert, David G.; McDonald, John; Regoli, Domenico; Salvadori, Severo Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 14 p. 5080 - 5095

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   3.3483
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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