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CS-W001157 4
Total: USD 88.00

Quinoline-6-boronic acid

  • CAS No. 376581-24-7

  • Cat. No. CS-D1096
  • Purity≥95%
  • MDL No.MFCD03093100

*For research and further manufacturing use only, not for direct human use.

Quinoline-6-boronic acid|CS-D1096

Structure of 376581-24-7

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General Information

  • CAS No. 376581-24-7
  • Cat. No. CS-D1096
  • Purity ≥95%
  • MDL No. MFCD03093100
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈BNO₂
  • Molecular Weight 172.98
  • Synonym(s) Quinoline-6-boronic Acid (contains varying amounts of Anhydride)
  • SMILES OB(O)C1=CC=C(N=CC=C2)C2=C1

Description

Quinoline-6-boronic acid integrates a boronate moiety at the 6-position of the quinoline scaffold, enabling direct functionalization in Suzuki-Miyaura coupling reactions. This bench-stable reagent features enhanced solubility in polar solvents and delivers efficient cross-coupling under mild conditions, streamlining access to complex heteroaryl architectures.

Application

Quinoline-6-boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki-Miyaura conditions. Its stability, ease of handling, and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic architectures in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.0854
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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