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CS-W001157 4
Total: USD 88.00

1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

  • CAS No. 375853-82-0

  • Cat. No. CS-0054178
  • Molecule weight209.09
  • Purity≥95%
  • MDL No.MFCD11506075

*For research and further manufacturing use only, not for direct human use.

1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine|CS-0054178

Structure of 375853-82-0

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General Information

  • CAS No. 375853-82-0
  • Cat. No. CS-0054178
  • Purity ≥95%
  • MDL No. MFCD11506075
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀BNO₂
  • Molecular Weight 209.09
  • Synonym(s) tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate
  • SMILES CC1(C)OB(OC1(C)C)C1=CCNCC1

Synthesis

  • Route1

    References

    • SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE; DUKE UNIVERSITY; PINKERTON, Anthony; MALONEY, Patrick; HERSHBERGER, Paul; PEDDIBHOTLA, Satyamaheshwar; HEDRICK, Michael; BARAK, Lawrence; CARON, Marc Patent: WO2014/100501 A1, 2014 ; Location in patent: Paragraph 00727; 00728 ;
  • Route2
    • null|null
      79099-07-3
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • ~97%
    • In-stock
      1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine|CS-0054178
      375853-82-0

    References

    • Yoshizumi, Takashi; Takahashi, Hirobumi; Miyazoe, Hiroshi; Sugimoto, Yuichi; Tsujita, Tomohiro; Kato, Tetsuya; Ito, Hirokatsu; Kawamoto, Hiroshi; Hirayama, Mioko; Ichikawa, Daisuke; Azuma-Kanoh, Tomoko; Ozaki, Satoshi; Shibata, Yoshihiro; Tani, Takeshi; Chiba, Masato; Ishii, Yasuyuki; Okuda, Shoki; Tadano, Kiyoshi; Fukuroda, Takahiro; Okamoto, Osamu; Ohta, Hisashi Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 4021 - 4029
  • Route3
    • 2,2'-Oxybis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)|CS-0805985
      10221-56-4
    • In-stock
      tert-Butyl 4-[(trifluoromethyl)sulfonyloxy]-5,6-dihydropyridine-1(2H)-carboxylate|CS-W019633
      138647-49-1
    • ~79%
    • In-stock
      1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine|CS-0054178
      375853-82-0

    References

    • Kim, Eunkyung; Park, Chan Sun; Han, Taedong; Bae, Myung-Ho; Chong, Wonee; Lee, Choong Hyun; Shin, Young Ah; Ahn, Byung-Nak; Kim, Mi Kyung; Shin, Chang Yell; Son, Moon Ho; Kim, Jin Kwan; Moon, Ho Sang; Shim, Hyun Joo; Kim, Eun Jung; Kim, Soon Hoe; Lim, Joong In; Lee, Chun Ho Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 18 p. 4993 - 4996

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   30.49
  • LogP   1.5375
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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