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tert-Butyl 4-(3-ethoxy-3-oxoprop-1-yn-1-yl)-4-hydroxypiperidine-1-carboxylate

  • CAS No. 374794-90-8

  • Cat. No. CS-B0359
  • Molecule weight297.35
  • Purity≥98%
  • MDL No.MFCD13184727

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(3-ethoxy-3-oxoprop-1-yn-1-yl)-4-hydroxypiperidine-1-carboxylate|CS-B0359

Structure of 374794-90-8

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General Information

  • CAS No. 374794-90-8
  • Cat. No. CS-B0359
  • Purity ≥98%
  • MDL No. MFCD13184727
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₃NO₅
  • Molecular Weight 297.35
  • Synonym(s) 1-Piperidinecarboxylic acid, 4-(3-ethoxy-3-oxo-1-propyn-1-yl)-4-hydroxy-, 1,1-dimethylethyl ester
  • SMILES O=C(OC(C)(C)C)N(CC1)CCC1(O)C#CC(OCC)=O

Synthesis

  • Route1
    • null|null
      79099-07-3
    • null|null
      623-47-2
    • ~%
    • tert-Butyl 4-(3-ethoxy-3-oxoprop-1-yn-1-yl)-4-hydroxypiperidine-1-carboxylate|CS-B0359
      374794-90-8

    References

    • Cooper, Laura C.; Carlson, Emma J.; Castro, Jose L.; Chicchi, Gary G.; Dinnell, Kevin; Di Salvo, Jerry; Elliott, Jason M.; Hollingworth, Gregory J.; Kurtz, Marc M.; Ridgill, Mark P.; Rycroft, Wayne; Tsao, Kwei-Lan; Swain, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 13 p. 1759 - 1762

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   1.3149
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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