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CS-W001157 4
Total: USD 88.00

(4-Cyclohexylphenyl)boronic acid

  • CAS No. 374538-04-2

  • Cat. No. CS-W015438
  • Purity≥98%
  • MDL No.MFCD02093068

*For research and further manufacturing use only, not for direct human use.

(4-Cyclohexylphenyl)boronic acid|CS-W015438

Structure of 374538-04-2

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General Information

  • CAS No. 374538-04-2
  • Cat. No. CS-W015438
  • Purity ≥98%
  • MDL No. MFCD02093068
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇BO₂
  • Molecular Weight 204.08
  • Synonym(s) 4-Cyclohexylphenylboronic acid
  • SMILES OB(O)C1=CC=C(C=C1)C1CCCCC1

Description

(4-Cyclohexylphenyl)boronic acid features a cyclohexyl-substituted aryl boronate moiety that enhances solubility and stability in organic media. This bench-stable reagent integrates readily into Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The bulky cyclohexyl group minimizes protodeboronation, improving functional group tolerance.

Application

(4-Cyclohexylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its cyclohexyl substituent imparts enhanced lipophilicity and metabolic stability, making it valuable for constructing biaryl motifs in pharmaceutical and agrochemical research. The boronic acid group exhibits excellent bench stability, tolerates common functional groups, and facilitates straightforward purification, supporting scalable synthesis and integration into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.4141
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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