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Structure of 3740-92-9
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4,6-Dichloro-2-phenylpyrimidine features a sterically hindered pyrimidine core with electron-withdrawing chloro groups at the 4 and 6 positions, paired with a phenyl substituent at the 2 position. This configuration enhances electrophilic reactivity and stability under standard conditions, enabling efficient coupling in cross-coupling and heterocycle formation reactions.
4,6-Dichloro-2-phenylpyrimidine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The dichloropyrimidine core exhibits high reactivity toward nucleophiles, facilitating the construction of complex heterocyclic scaffolds with predictable regioselectivity. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring robust functional group tolerance and compatibility with diverse reaction conditions.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: