Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-((Trifluoromethyl)thio)aniline

  • CAS No. 372-16-7

  • Cat. No. CS-W015778
  • Molecule weight193.19
  • Purity≥98%
  • MDL No.MFCD00040926

*For research and further manufacturing use only, not for direct human use.

4-((Trifluoromethyl)thio)aniline|CS-W015778

Structure of 372-16-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 372-16-7
  • Cat. No. CS-W015778
  • Purity ≥98%
  • MDL No. MFCD00040926
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆F₃NS
  • Molecular Weight 193.19
  • Synonym(s) 4-Aminophenyl trifluoromethyl sulphide
  • SMILES NC1=CC=C(SC(F)(F)F)C=C1

Description

4-((Trifluoromethyl)thio)aniline features a trifluoromethylthio group positioned para to the amino functionality, imparting enhanced electron-withdrawing character and improved metabolic stability. This configuration enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring high lipophilicity and resistance to oxidative degradation.

Application

4-((Trifluoromethyl)thio)aniline serves as a valuable building block in medicinal chemistry, enabling the introduction of a strongly electron-withdrawing trifluoromethylthio group at the para position of an aromatic ring. Its robust bench stability and compatibility with standard coupling reactions facilitate efficient incorporation into diverse heterocyclic scaffolds and API intermediates. The functional group exhibits high tolerance to varied reaction conditions, supporting its use in multi-step syntheses requiring selective transformations.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.8807
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-((Trifluoromethyl)thio)aniline sigma4-((Trifluoromethyl)thio)aniline manufacturer4-((Trifluoromethyl)thio)aniline price4-((Trifluoromethyl)thio)aniline structure4-((Trifluoromethyl)thio)aniline SDSbuy 4-((Trifluoromethyl)thio)aniline4-((Trifluoromethyl)thio)aniline supplier4-((Trifluoromethyl)thio)aniline uses4-((Trifluoromethyl)thio)aniline molecular weightprice of 4-((Trifluoromethyl)thio)aniline4-((Trifluoromethyl)thio)aniline chemical name formula of 4-((Trifluoromethyl)thio)aniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label