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Structure of 3699-67-0
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Ethyl 3-(diethoxyphosphoryl)propanoate serves as a key phosphonate synthon in C–C bond formation, featuring a reactive diethylphosphoryl group flanked by an ester and methylene units. This stable, bench-ready reagent enables efficient Horner–Wadsworth–Emmons reactions and integrates readily into synthetic sequences requiring controlled phosphorus incorporation.
Ethyl 3-(diethoxyphosphoryl)propanoate serves as a versatile synthon in carbonyl-alkylation and Michael addition reactions, enabling efficient construction of γ-functionalized carbonyl compounds. Its stable diethoxyphosphoryl group facilitates reliable enolization and subsequent C–C bond formation under mild conditions. The molecule exhibits excellent bench stability, ease of purification, and compatibility with common protecting groups, making it a practical choice for iterative synthesis of complex intermediates in medicinal chemistry and natural product workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: