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CS-W001157 4
Total: USD 88.00

1-Methyl-1H-pyrrole-3-carboxylic acid

  • CAS No. 36929-61-0

  • Cat. No. CS-W003777
  • Purity≥97%
  • MDL No.MFCD11111733

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-pyrrole-3-carboxylic acid|CS-W003777

Structure of 36929-61-0

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General Information

  • CAS No. 36929-61-0
  • Cat. No. CS-W003777
  • Purity ≥97%
  • MDL No. MFCD11111733
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO₂
  • Molecular Weight 125.13
  • Synonym(s) 1H-PYRROLE-3-CARBOXYLIC ACID, 1-METHYL-
  • SMILES O=C(C1=CN(C)C=C1)O

Description

1-Methyl-1H-pyrrole-3-carboxylic acid features a methyl-substituted pyrrole core with a carboxylic acid at the C3 position, delivering enhanced solubility and stability compared to unsubstituted analogs. This scaffold integrates readily into heterocyclic libraries for medicinal chemistry, offering a polar, electron-rich platform suitable for coupling reactions and bioactive molecule design under standard conditions.

Application

1-Methyl-1H-pyrrole-3-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, offering a readily accessible pyrrole scaffold with orthogonal functionalization potential. The carboxylic acid group enables direct amidation, esterification, or coupling reactions, while the methyl-substituted pyrrole ring provides enhanced stability and tunable electronic properties. Its bench-stable nature and compatibility with standard peptide and cross-coupling protocols facilitate efficient incorporation into complex molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   42.23
  • LogP   0.7233
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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