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CS-W001157 4
Total: USD 88.00

trans-4-Hydroxycyclohexanecarboxylic acid

  • CAS No. 3685-26-5

  • Cat. No. CS-M0763
  • Purity≥97%
  • MDL No.MFCD02093477

*For research and further manufacturing use only, not for direct human use.

trans-4-Hydroxycyclohexanecarboxylic acid|CS-M0763

Structure of 3685-26-5

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General Information

  • CAS No. 3685-26-5
  • Cat. No. CS-M0763
  • Purity ≥97%
  • MDL No. MFCD02093477
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O₃
  • Molecular Weight 144.17
  • Synonym(s) None
  • SMILES OC([C@H]1CC[C@@H](CC1)O)=O

Description

trans-4-Hydroxycyclohexanecarboxylic acid features a rigid cyclohexane scaffold with spatially defined hydroxyl and carboxylic acid groups. This stereochemically controlled arrangement enhances its utility in asymmetric synthesis and as a chiral building block for bioactive molecule development. The compound exhibits bench-stable handling characteristics and integrates readily into diverse functionalization workflows.

Application

trans-4-Hydroxycyclohexanecarboxylic acid serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and cyclic peptide scaffolds. Its well-defined stereochemistry and bench-stable carboxylic acid functionality facilitate efficient derivatization, including amide coupling and esterification, with high functional group tolerance. The molecule’s rigid cyclohexane core provides conformational control, enhancing target binding affinity in drug discovery campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   0.6221
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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