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CS-W001157 4
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(2-(1H-indol-3-yl)acetyl)-L-leucine

  • CAS No. 36838-63-8

  • Cat. No. CS-0451748
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-(1H-indol-3-yl)acetyl)-L-leucine|CS-0451748

Structure of 36838-63-8

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General Information

  • CAS No. 36838-63-8
  • Cat. No. CS-0451748
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₀N₂O₃
  • Molecular Weight 288.34
  • Synonym(s) N-(3-Indolylacetyl)-L-leucine
  • SMILES CC(C[C@H](NC(CC1=CNC2=CC=CC=C12)=O)C(O)=O)C

Description

This indole-acetyl leucine derivative integrates a biologically relevant indole motif with a hydrophobic leucine scaffold, enabling selective incorporation into peptide sequences. The (2-(1H-indol-3-yl)acetyl) moiety enhances membrane permeability and target engagement, while the L-leucine residue supports conformational stability in synthetic peptides.

Synthesis

  • Route1

    References

    • Justus Liebigs Annalen der Chemie, , vol. 591, p. 192,198

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   82.19
  • LogP   2.3259
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   6

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