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CS-W001157 4
Total: USD 88.00

Tetrabutylammonium thiocyanate

  • CAS No. 3674-54-2

  • Cat. No. CS-0179389
  • Molecule weight300.55
  • Purity≥95%
  • MDL No.MFCD00012140

*For research and further manufacturing use only, not for direct human use.

Tetrabutylammonium thiocyanate|CS-0179389

Structure of 3674-54-2

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General Information

  • CAS No. 3674-54-2
  • Cat. No. CS-0179389
  • Purity ≥95%
  • MDL No. MFCD00012140
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₃₆N₂S
  • Molecular Weight 300.55
  • Synonym(s) None
  • SMILES CCCC[N+](CCCC)(CCCC)CCCC.[S-]C#N

Description

Tetrabutylammonium thiocyanate delivers a soluble, bench-stable source of thiocyanate anions for use in nucleophilic substitution and phase-transfer catalysis. The bulky tetraalkylammonium cation enhances solubility in organic media while minimizing ion pairing, enabling efficient anion transfer across biphasic interfaces. This reagent facilitates reactions requiring soft nucleophiles under mild conditions.

Application

Tetrabutylammonium thiocyanate serves as a versatile phase-transfer catalyst and source of nucleophilic thiocyanate in organic synthesis. It facilitates cyanation reactions, promotes halide exchange processes, and enhances solubility of ionic reagents in nonpolar media. Its stability under ambient conditions and ease of purification make it well-suited for bench-scale applications in heterocycle construction and functional group interconversions.

Synthesis

  • Route1

    References

    • Thermochimica Acta, , vol. 556, p. 23 - 29
  • Route2
    • In-stock
      Tetrabutylammonium bromide|CS-0010099
      1643-19-2
    • null|null
      333-20-0
    • ~95%
    • In-stock
      Tetrabutylammonium thiocyanate|CS-0179389
      3674-54-2

    References

    • Dehmlow, Eckehard V.; Vehre, Burkhard; Broda, Witold Synthesis, 1985 , # 5 p. 508 - 509
  • Route3
    • null|null
      10544-50-0
    • null|null
      10442-39-4
    • ~%
    • In-stock
      Tetrabutylammonium thiocyanate|CS-0179389
      3674-54-2

    References

    • Inorganic Chemistry, , vol. 27, p. 749 - 752

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.79
  • LogP   5.01798
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   12

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