Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Amino-2,3-dihydro-1H-isoindol-1-one

  • CAS No. 366452-98-4

  • Cat. No. CS-0051053
  • Purity≥98%
  • MDL No.MFCD08234883

*For research and further manufacturing use only, not for direct human use.

4-Amino-2,3-dihydro-1H-isoindol-1-one|CS-0051053

Structure of 366452-98-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 366452-98-4
  • Cat. No. CS-0051053
  • Purity ≥98%
  • MDL No. MFCD08234883
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂O
  • Molecular Weight 148.16
  • Synonym(s) 4-Aminoisoindolin-1-one
  • SMILES NC1=C2CNC(=O)C2=CC=C1

Description

4-Amino-2,3-dihydro-1H-isoindol-1-one features a fused bicyclic core with a pendant primary amine and carbonyl group, enabling direct incorporation into bioactive molecule scaffolds. This bench-stable heterocycle serves as a key building block in medicinal chemistry, particularly for targeting kinase pathways and modulating protein-protein interactions.

Application

4-Amino-2,3-dihydro-1H-isoindol-1-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to biologically relevant heterocycles. Its amine and carbonyl functionalities support diverse transformations, including amidation, alkylation, and coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development and target-oriented discovery.

Synthesis

  • Route1

    References

    • NANJING CAVENDISH BIO-ENGINEERING TECHNOLOGY CO., LTD.; YAN, Rong; YANG, Hao; XU, Yongxiang Patent: WO2010/139266 A1, 2010 ; Location in patent: Page/Page column 38-39 ;
  • Route2
    • null|null
      825655-17-2
    • ~64%
    • In-stock
      4-Amino-2,3-dihydro-1H-isoindol-1-one|CS-0051053
      366452-98-4

    References

    • SCHERING AKTIENGESELLSCHAFT Patent: WO2005/3098 A1, 2005 ; Location in patent: Page/Page column 94 ;
  • Route3
    • null|null
      825655-17-2
    • null|null
      1333-74-0
    • ~64%
    • In-stock
      4-Amino-2,3-dihydro-1H-isoindol-1-one|CS-0051053
      366452-98-4

    References

    • SCHERING AKTIENGESELLSCHAFT Patent: WO2005/34939 A1, 2005 ; Location in patent: Page/Page column 53; 54 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.5122
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Amino-2,3-dihydro-1H-isoindol-1-one sigma4-Amino-2,3-dihydro-1H-isoindol-1-one manufacturer4-Amino-2,3-dihydro-1H-isoindol-1-one price4-Amino-2,3-dihydro-1H-isoindol-1-one structure4-Amino-2,3-dihydro-1H-isoindol-1-one SDSbuy 4-Amino-2,3-dihydro-1H-isoindol-1-one4-Amino-2,3-dihydro-1H-isoindol-1-one supplier4-Amino-2,3-dihydro-1H-isoindol-1-one uses4-Amino-2,3-dihydro-1H-isoindol-1-one molecular weightprice of 4-Amino-2,3-dihydro-1H-isoindol-1-one4-Amino-2,3-dihydro-1H-isoindol-1-one chemical name formula of 4-Amino-2,3-dihydro-1H-isoindol-1-one
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label