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CS-W001157 4
Total: USD 88.00

a-Tosylbenzyl isocyanide

  • CAS No. 36635-66-2

  • Cat. No. CS-0622113
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

a-Tosylbenzyl isocyanide|CS-0622113

Structure of 36635-66-2

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General Information

  • CAS No. 36635-66-2
  • Cat. No. CS-0622113
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₃NO₂S
  • Molecular Weight 271.33
  • Synonym(s) None
  • SMILES CC1=CC=C(C=C1)S(=O)(=O)C(C2=CC=CC=C2)[N+]#[C-]

Description

a-Tosylbenzyl isocyanide features a tosyl-substituted benzyl group linked to an isocyanide moiety, delivering enhanced stability and solubility in organic media. This combination enables efficient coordination in transition metal catalysis and facilitates the synthesis of complex heterocycles under mild conditions.

Application

a-Tosylbenzyl isocyanide serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions and heterocycle synthesis. Its tosyl-protected benzylic isocyanide functionality enables selective reactivity in Pd- or Ni-catalyzed C–N bond formations, facilitates efficient access to substituted benzimidazoles and triazoles, and offers enhanced bench stability compared to unprotected analogs. The robust tosyl group provides excellent functional group tolerance and simplifies purification in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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