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3-Amino-5-methylhexanoic acid

  • CAS No. 3653-34-7

  • Cat. No. CS-W021839
  • Purity≥97%
  • MDL No.MFCD01863281

*For research and further manufacturing use only, not for direct human use.

3-Amino-5-methylhexanoic acid|CS-W021839

Structure of 3653-34-7

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General Information

  • CAS No. 3653-34-7
  • Cat. No. CS-W021839
  • Purity ≥97%
  • MDL No. MFCD01863281
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅NO₂
  • Molecular Weight 145.20
  • Synonym(s) (±)-3-Amino-5-methylhexanoic Acid
  • SMILES CC(C)CC(N)CC(O)=O

Description

3-Amino-5-methylhexanoic acid features a branched aliphatic chain with strategically positioned amino and carboxylic acid functional groups. This structure supports integration into peptide backbones and bioconjugation workflows, offering enhanced solubility and metabolic stability in synthetic intermediates.

Application

3-Amino-5-methylhexanoic acid serves as a versatile chiral building block for peptide-based synthesis and bioactive molecule construction. Its amino and carboxylic acid functionalities enable straightforward coupling reactions, while the branched alkyl chain provides steric differentiation and metabolic stability. The compound exhibits good bench stability and facilitates efficient purification via standard ion-exchange or reverse-phase chromatography, making it well-suited for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      136918-14-4
    • Diethyl 2-(3-methylbutylidene)malonate|CS-0511268
      51615-30-6
    • ~%
    • In-stock
      3-Amino-5-methylhexanoic acid|CS-W021839
      3653-34-7

    References

    • Chimija chim.Technol.(NDVS)Chem.Abstr., , p. 545 Chimija chim.Technol.(NDVS)Chem.Abstr., , p. 2149

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.8345
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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