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CS-W001157 4
Total: USD 88.00

1-[2-(Dimethylamino)ethyl]piperazine

  • CAS No. 3644-18-6

  • Cat. No. CS-0106269
  • Purity≥98%
  • MDL No.MFCD00167969

*For research and further manufacturing use only, not for direct human use.

1-[2-(Dimethylamino)ethyl]piperazine|CS-0106269

Structure of 3644-18-6

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General Information

  • CAS No. 3644-18-6
  • Cat. No. CS-0106269
  • Purity ≥98%
  • MDL No. MFCD00167969
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₉N₃
  • Molecular Weight 157.26
  • Synonym(s) 1-(2-Dimethylaminoethyl)piperazine
  • SMILES CN(C)CCN1CCNCC1

Description

1-[2-(Dimethylamino)ethyl]piperazine is a bifunctional amine featuring a piperazine core appended with a dimethylaminoethyl side chain. This structure delivers enhanced solubility and nucleophilicity, enabling efficient conjugation in peptide synthesis and polymer functionalization. The molecule exhibits robust stability under standard bench conditions and facilitates rapid reaction kinetics in amine-coupling workflows.

Application

1-[2-(Dimethylamino)ethyl]piperazine serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient conjugation via its primary amine and secondary amine functionalities. Its dimethylaminoethyl side chain enhances solubility and facilitates salt formation, while the piperazine core provides a rigid yet tunable scaffold for bioactive molecule design. The compound exhibits good bench stability and compatibility with standard coupling reactions, making it ideal for modular synthesis of targeted therapeutics and functionalized intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.51
  • LogP   -0.5468
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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