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Structure of 364-11-4
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1-Bromo-4-iodo-2-(trifluoromethyl)benzene features a trifluoromethyl group flanked by bromo and iodo substituents, enabling sequential cross-coupling reactions. This electron-deficient aromatic scaffold integrates readily into complex molecular architectures under standard conditions.
1-Bromo-4-iodo-2-(trifluoromethyl)benzene serves as a versatile bifunctional aryl building block for palladium-catalyzed cross-coupling reactions. The bromo and iodo groups enable sequential or orthogonal coupling processes, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity—key attributes in medicinal chemistry. Bench-stable and readily purified by column chromatography, it facilitates efficient construction of complex biaryl scaffolds and functionalized heterocycles in multi-step synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: