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CS-W001157 4
Total: USD 88.00

(2,6-Diisopropylphenyl)boronic acid

  • CAS No. 363166-79-4

  • Cat. No. CS-0081231
  • Purity≥96%
  • MDL No.MFCD16876786

*For research and further manufacturing use only, not for direct human use.

(2,6-Diisopropylphenyl)boronic acid|CS-0081231

Structure of 363166-79-4

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General Information

  • CAS No. 363166-79-4
  • Cat. No. CS-0081231
  • Purity ≥96%
  • MDL No. MFCD16876786
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₉BO₂
  • Molecular Weight 206.09
  • Synonym(s) 2,6-Diisopropylphenylboronic acid
  • SMILES OB(C1=C(C(C)C)C=CC=C1C(C)C)O

Description

This boronate moiety features a sterically shielded arylboronic acid scaffold, enabling robust coupling in Suzuki-Miyaura reactions. The ortho-diisopropyl substitution enhances stability and solubility under standard conditions, minimizing protodeboronation while facilitating efficient cross-coupling with diverse electrophiles.

Application

(2,6-Diisopropylphenyl)boronic acid serves as a robust arylboron building block for Suzuki-Miyaura cross-coupling reactions. Its sterically hindered ortho-diisopropyl substitution enhances stability and minimizes protodeboronation, enabling reliable coupling under mild conditions. The compound exhibits excellent functional group tolerance and facilitates efficient access to complex biaryl architectures in medicinal chemistry and materials synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.6132
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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