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CS-W001157 4
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1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine

  • CAS No. 36314-47-3

  • Cat. No. CS-0138226
  • Purity≥98%
  • MDL No.MFCD00066564

*For research and further manufacturing use only, not for direct human use.

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine|CS-0138226

Structure of 36314-47-3

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General Information

  • CAS No. 36314-47-3
  • Cat. No. CS-0138226
  • Purity ≥98%
  • MDL No. MFCD00066564
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₀H₈₄NO₆P
  • Molecular Weight 706.07
  • Synonym(s) 16:0 Diether PC
  • SMILES CCCCCCCCCCCCCCCCOC[C@@H](OCCCCCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O

Description

Ether-linked 16:0 diether PC (CAS 36314-47-3) stabilizes lipid bilayer architecture through sn-1/sn-2 glycerol ether tethering, maintaining membrane fluidity in synthetic vesicle systems under oxidative stress.

Application

16:0 Diether PC (CAS 36314-47-3) drives studies on cationic EDPPC miscibility and phase transitions within unilamellar vesicles by providing a defined ether-linked phosphocholine scaffold. It enables precise lipid matrix comparisons. Researchers leverage this stable, non-ladderane reference to isolate glycolipid transfer dynamics via GLTP assays. This setup streamlines reversed-phase LC separations of complex PC lipid mixtures. It also facilitates bicelle formation for high-resolution solid-state NMR analysis of HIV-1 Vpu’s transmembrane domain architecture.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   77.05
  • LogP   11.5586
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   40

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