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Structure of 36293-63-7
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tert-Butyl 2-hydroxy-2-methylpropanoate features a sterically hindered tertiary alcohol moiety that enhances stability under acidic conditions. This bench-stable ester serves as a protected hydroxy precursor in synthetic sequences, enabling controlled deprotection and functional group interconversions. The tert-butyl group facilitates efficient isolation and purification, while the alpha-hydroxy functionality supports downstream derivatization in complex molecule assembly.
tert-Butyl 2-hydroxy-2-methylpropanoate serves as a stable, bench-friendly building block for the synthesis of α-hydroxy carboxylic acid derivatives. Its tertiary ester functionality enables selective hydrolysis under mild acidic conditions, facilitating access to the corresponding carboxylic acid with retained stereochemical integrity. The molecule exhibits excellent functional group tolerance and simplifies purification due to its low polarity and high crystallinity, making it well-suited for use in iterative synthetic sequences and complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 3272
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501
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Lot numbers can be found on the outside label of a product: