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CS-W001157 4
Total: USD 88.00

tert-Butyl 2-hydroxy-2-methylpropanoate

  • CAS No. 36293-63-7

  • Cat. No. CS-0227378
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2-hydroxy-2-methylpropanoate|CS-0227378

Structure of 36293-63-7

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Description

tert-Butyl 2-hydroxy-2-methylpropanoate features a sterically hindered tertiary alcohol moiety that enhances stability under acidic conditions. This bench-stable ester serves as a protected hydroxy precursor in synthetic sequences, enabling controlled deprotection and functional group interconversions. The tert-butyl group facilitates efficient isolation and purification, while the alpha-hydroxy functionality supports downstream derivatization in complex molecule assembly.

Application

tert-Butyl 2-hydroxy-2-methylpropanoate serves as a stable, bench-friendly building block for the synthesis of α-hydroxy carboxylic acid derivatives. Its tertiary ester functionality enables selective hydrolysis under mild acidic conditions, facilitating access to the corresponding carboxylic acid with retained stereochemical integrity. The molecule exhibits excellent functional group tolerance and simplifies purification due to its low polarity and high crystallinity, making it well-suited for use in iterative synthetic sequences and complex molecule assembly.

General Information

  • CAS No. 36293-63-7
  • Cat. No. CS-0227378
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆O₃
  • Molecular Weight 160.21
  • Synonym(s) TERT-BUTYL ALPHA-HYDROXYISOBUTYRATE
  • SMILES CC(C)(O)C(OC(C)(C)C)=O

Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.099
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 3272
Class : 3
Packing Group :
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

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