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tert-Butyl (2-amino-5-fluorophenyl)carbamate

  • CAS No. 362670-07-3

  • Cat. No. CS-0038835
  • Purity≥95%
  • MDL No.MFCD07787180

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-amino-5-fluorophenyl)carbamate|CS-0038835

Structure of 362670-07-3

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General Information

  • CAS No. 362670-07-3
  • Cat. No. CS-0038835
  • Purity ≥95%
  • MDL No. MFCD07787180
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅FN₂O₂
  • Molecular Weight 226.25
  • Synonym(s) N2-Boc-4-fluoro-1,2-phenylenediamine
  • SMILES CC(C)(OC(NC1=CC(F)=CC=C1N)=O)C

Synthesis

  • Route1

    References

    • ABBOTT LABORATORIES; ENANTA PHARMACEUTICALS, INC.; CHEN, Hui-ju; MCDANIEL, Keith, F.; GREEN, Brian, E.; SHANLEY, Jason, P.; KRUGER, Albert, W.; GANDARILLA, Jorge; WELCH, Dennie, S.; CINK, Russell, D.; GAI, Yonghua; WANG, Guoqiang; OR, Yat, Sun Patent: WO2011/156337 A2, 2011 ; Location in patent: Page/Page column 209-210 ; WO 2011/156337 A2
  • Route2

    References

    • ABBOTT LABORATORIES; ENANTA PHARMACEUTICALS, INC.; CHEN, Hui-ju; MCDANIEL, Keith, F.; GREEN, Brian, E.; SHANLEY, Jason, P.; KRUGER, Albert, W.; GANDARILLA, Jorge; WELCH, Dennie, S.; CINK, Russell, D.; GAI, Yonghua; WANG, Guoqiang; OR, Yat, Sun Patent: WO2011/156337 A2, 2011 ; WO 2011/156337 A2
  • Route3

    References

    • ABBOTT LABORATORIES; ENANTA PHARMACEUTICALS, INC.; CHEN, Hui-ju; MCDANIEL, Keith, F.; GREEN, Brian, E.; SHANLEY, Jason, P.; KRUGER, Albert, W.; GANDARILLA, Jorge; WELCH, Dennie, S.; CINK, Russell, D.; GAI, Yonghua; WANG, Guoqiang; OR, Yat, Sun Patent: WO2011/156337 A2, 2011 ; WO 2011/156337 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.7549
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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