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CS-W001157 4
Total: USD 88.00

1,6-Naphthyridine-8-carboxylic acid

  • CAS No. 362606-19-7

  • Cat. No. CS-0072548
  • Purity≥97%
  • MDL No.MFCD09863867

*For research and further manufacturing use only, not for direct human use.

1,6-Naphthyridine-8-carboxylic acid|CS-0072548

Structure of 362606-19-7

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General Information

  • CAS No. 362606-19-7
  • Cat. No. CS-0072548
  • Purity ≥97%
  • MDL No. MFCD09863867
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆N₂O₂
  • Molecular Weight 174.16
  • Synonym(s) None
  • SMILES O=C(O)C1=CN=CC2=CC=CN=C12

Description

1,6-Naphthyridine-8-carboxylic acid features a rigid, electron-deficient heteroaromatic core paired with a carboxylic acid handle, enabling direct conjugation in synthetic transformations. This scaffold integrates seamlessly into bioactive molecule design, offering enhanced solubility and metabolic stability in medicinal chemistry applications.

Application

1,6-Naphthyridine-8-carboxylic acid serves as a versatile scaffold for medicinal chemistry and catalytic applications, offering a rigid, electron-deficient heterocyclic core with orthogonal functionalization potential. The carboxylic acid group enables direct amidation, esterification, or metal chelation, facilitating conjugation to peptides, polymers, or transition metal complexes. Bench-stable and readily purified by recrystallization, it functions reliably in standard coupling protocols and is compatible with diverse reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   63.08
  • LogP   1.328
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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