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CS-W001157 4
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6-Methoxy-1-naphthoic acid

  • CAS No. 36112-61-5

  • Cat. No. CS-0043045
  • Purity≥97%
  • MDL No.MFCD00090331

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-1-naphthoic acid|CS-0043045

Structure of 36112-61-5

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General Information

  • CAS No. 36112-61-5
  • Cat. No. CS-0043045
  • Purity ≥97%
  • MDL No. MFCD00090331
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₀O₃
  • Molecular Weight 202.21
  • Synonym(s) 6-methoxynaphthalene-1-carboxylic acid
  • SMILES O=C(O)C1=C2C=CC(OC)=CC2=CC=C1

Description

6-Methoxy-1-naphthoic acid features a naphthoic acid core with a methoxy group at the 6-position, enhancing solubility and modulating electronic properties. This configuration supports efficient coupling reactions in synthetic pathways, particularly in pharmaceutical intermediates and functional materials. The compound exhibits stability under standard conditions and facilitates regioselective transformations.

Application

6-Methoxy-1-naphthoic acid serves as a versatile building block for the synthesis of functionalized naphthalene derivatives. Its carboxylic acid group enables direct amidation, esterification, and coupling reactions, while the 6-methoxy substituent provides regioselective electronic modulation and enhanced solubility. The compound exhibits excellent bench stability and facilitates purification via recrystallization, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.5466
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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