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CS-W001157 4
Total: USD 88.00

Diethyl 2,2'-(1,4-phenylene)diacetate

  • CAS No. 36076-26-3

  • Cat. No. CS-W012641
  • Purity≥98%
  • MDL No.MFCD00032366

*For research and further manufacturing use only, not for direct human use.

Diethyl 2,2'-(1,4-phenylene)diacetate|CS-W012641

Structure of 36076-26-3

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General Information

  • CAS No. 36076-26-3
  • Cat. No. CS-W012641
  • Purity ≥98%
  • MDL No. MFCD00032366
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈O₄
  • Molecular Weight 250.29
  • Synonym(s) 1,4-Phenylenediacetic Acid Diethyl Ester
  • SMILES CCOC(=O)CC1=CC=C(CC(=O)OCC)C=C1

Description

Diethyl 2,2'-(1,4-phenylene)diacetate features a rigid para-phenylene spacer linking two ester-functionalized acetic acid units. This symmetric architecture enables efficient coupling in cross-coupling reactions and provides a stable scaffold for building conjugated systems in materials science applications.

Application

Diethyl 2,2'-(1,4-phenylene)diacetate serves as a versatile bis-ester building block for the synthesis of aromatic diacids and functionalized polyesters. Its robust bench stability and compatibility with standard hydrolysis and coupling reactions enable efficient access to symmetric phenylene-linked scaffolds. The molecule facilitates reliable ester cleavage under mild conditions and functions effectively in condensation polymerizations and metal-catalyzed cross-coupling workflows.

Synthesis

  • Route1
    • null|null
      64-17-5
    • In-stock
      1,4-Benzenediacetic acid|CS-W010662
      7325-46-4
    • ~88%
    • In-stock
      Diethyl 2,2'-(1,4-phenylene)diacetate|CS-W012641
      36076-26-3

    References

    • An, Peng; Shi, Zi-Fa; Dou, Wei; Cao, Xiao-Ping; Zhang, Hao-Li Organic Letters, 2010 , vol. 12, # 19 p. 4364 - 4367
  • Route2

    References

    • Ke, Jie; He, Chuan; Liu, Huiying; Xu, Huan; Lei, Aiwen Chemical Communications, 2013 , vol. 49, # 60 p. 6767 - 6769
  • Route3
    • null|null
      105077-01-8
    • ~86%
    • In-stock
      Diethyl 2,2'-(1,4-phenylene)diacetate|CS-W012641
      36076-26-3

    References

    • Ishibashi, Hiroyuki; Ikeda, Masazumi; Choi, Hong Dae; Nakagawa, Hiroko; Ueda, Yuko; Tamura, Yasumitsu Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 12 p. 5310 - 5315

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.8978
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   6

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