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CS-W001157 4
Total: USD 88.00

3-Bromopicolinamide

  • CAS No. 36057-54-2

  • Cat. No. CS-0149986
  • Purity≥98%
  • MDL No.MFCD11043941

*For research and further manufacturing use only, not for direct human use.

3-Bromopicolinamide|CS-0149986

Structure of 36057-54-2

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General Information

  • CAS No. 36057-54-2
  • Cat. No. CS-0149986
  • Purity ≥98%
  • MDL No. MFCD11043941
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrN₂O
  • Molecular Weight 201.02
  • Synonym(s) 3-BROMO-PYRIDINE-2-CARBOXYLIC ACID AMIDE
  • SMILES NC(C1=C(Br)C=CC=N1)=O

Description

3-Bromopicolinamide features a bromine-substituted pyridine ring paired with an amide functionality, enabling direct incorporation into diverse heterocyclic scaffolds. This bench-stable derivative serves as a key intermediate in medicinal chemistry and materials synthesis, where its halogen handle supports palladium-catalyzed coupling reactions and its polar amide group enhances solubility and molecular recognition.

Application

3-Bromopicolinamide serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromo substituent at the pyridine ring. The amide functionality provides enhanced solubility and stability compared to ester analogs, facilitating purification and downstream derivatization. Its compatibility with standard coupling protocols makes it a reliable scaffold for constructing bioactive heterocycles and functionalized aromatic compounds in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   55.98
  • LogP   0.943
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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