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CS-W001157 4
Total: USD 88.00

Propofol impurity 1

  • CAS No. 35946-91-9

  • Cat. No. CS-0154292
  • Purity≥95%
  • MDL No.MFCD00026396

*For research and further manufacturing use only, not for direct human use.

Propofol impurity 1|CS-0154292

Structure of 35946-91-9

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General Information

  • CAS No. 35946-91-9
  • Cat. No. CS-0154292
  • Purity ≥95%
  • MDL No. MFCD00026396
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈O
  • Molecular Weight 178.27
  • Synonym(s) None
  • SMILES CC(C)C1=CC(=C(C=C1)C(C)C)O

Application

2,5-Diisopropylphenol serves as a valuable aryl building block in synthetic organic chemistry, offering enhanced steric bulk and thermal stability due to its ortho-isopropyl substituents. It facilitates efficient functionalization at the para position and functions reliably in electrophilic substitution and coupling reactions. The molecule exhibits excellent bench stability and ease of purification, making it well-suited for use in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • 2,5-Diisopropylaniline|CS-0753880
      91552-65-7
    • ~%
    • null|null
      33685-58-4
    • In-stock
      Propofol impurity 1|CS-0154292
      35946-91-9

    References

    • Mukawa, Takashi; Inoue, Yukihiko; Shiraishi, Shinsaku Bulletin of the Chemical Society of Japan, 1999 , vol. 72, # 11 p. 2549 - 2556
  • Route2
    • 2-Bromo-1,4-diisopropylbenzene|CS-1694763
      42196-29-2
    • ~%
    • In-stock
      Propofol impurity 1|CS-0154292
      35946-91-9

    References

    • Dow Chem. Co. Patent: US2207753 , 1937 ;
  • Route3
    • null|null
      106-44-5
    • null|null
      75-29-6
    • ~%
    • In-stock
      Propofol impurity 1|CS-0154292
      35946-91-9

    References

    • Dewar,M.J.S.; Puttnam,N.A. Journal of the Chemical Society, 1960 , p. 959 - 963

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   3.639
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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