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Structure of 35808-45-8
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Pyrido[2,3-b]pyrazin-6(5H)-one delivers a rigid, electron-deficient heterocyclic scaffold ideal for medicinal chemistry applications. This planar core integrates seamlessly into kinase inhibitors and targeted therapeutics, offering enhanced binding affinity through π-stacking interactions and improved metabolic stability in biological assays.
Pyrido[2,3-b]pyrazin-6(5H)-one serves as a versatile heterocyclic building block in medicinal chemistry, featuring a fused tricyclic scaffold with defined nitrogen positioning. Its amphoteric character and hydrogen-bonding capacity enable robust interactions in target binding, while its stability under standard synthetic conditions facilitates functionalization at multiple sites. The core structure participates reliably in nucleophilic substitution and transition-metal-catalyzed coupling reactions, making it a practical foundation for diversification in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: