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Structure of 35674-27-2
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4-Iodo-3-nitrobenzoic acid features a sterically accessible carboxylic acid group flanked by electron-withdrawing iodine and nitro substituents, enabling direct functionalization in cross-coupling and conjugation workflows under standard conditions.
4-Iodo-3-nitrobenzoic acid serves as a versatile building block for Suzuki-Miyaura and Negishi coupling reactions, enabling efficient access to biaryl scaffolds under mild conditions. The iodine functionality exhibits high reactivity and compatibility with palladium-catalyzed cross-couplings, while the nitro group provides orthogonal handle for subsequent reduction or further functionalization. Bench-stable and readily purified by recrystallization, it facilitates reproducible synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: