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CS-W001157 4
Total: USD 88.00

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

  • CAS No. 35480-52-5

  • Cat. No. CS-M0605
  • Purity≥98%
  • MDL No.MFCD00221424

*For research and further manufacturing use only, not for direct human use.

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid|CS-M0605

Structure of 35480-52-5

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General Information

  • CAS No. 35480-52-5
  • Cat. No. CS-M0605
  • Purity ≥98%
  • MDL No. MFCD00221424
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈F₆O₄
  • Molecular Weight 318.17
  • Synonym(s) 2,4-DICHLORO-5-DIETHYLSULFAMOYL-BENZOIC ACID
  • SMILES O=C(O)C(C=C1OCC(F)(F)F)=C(C=C1)OCC(F)(F)F

Description

2-Ethoxyethyl acetate is used as a solvent dissolve resin, leather, ink, for the formulation of paints, lacquers and varnishes for industrial use. It is also used to study the field evaluation of a passive badge for measuring 2-ethoxyethyl acetate.

Application

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid serves as a valuable building block in medicinal chemistry, enabling the introduction of highly lipophilic and metabolically stable trifluoroethoxy groups into aromatic scaffolds. Its carboxylic acid functionality facilitates direct coupling reactions or derivatization, while the ortho-substituted trifluoroethoxy moieties enhance electron-withdrawing character and influence molecular conformation. The compound exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthesis campaigns targeting bioactive heterocycles and drug candidates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   3.267
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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