(R)-2-Amino-2-(4-bromophenyl)ethan-1-ol

Name: (R)-2-Amino-2-(4-bromophenyl)ethan-1-ol
Brand: ChemScene
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CAS No. 354153-64-3
Cat. No. CS-0131603
Purity≥97%
MDL No.MFCD09256373

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-Amino-2-(4-bromophenyl)ethan-1-ol|CS-0131603

Structure of 354153-64-3

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General Information

CAS No. 354153-64-3
Cat. No. CS-0131603
Purity ≥97%
MDL No. MFCD09256373
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀BrNO
Molecular Weight 216.08
Synonym(s) (R)-2-Amino-2-(4-bromophenyl)ethanol
SMILES BrC1=CC=C([C@@H](N)CO)C=C1

Description

(R)-2-Amino-2-(4-bromophenyl)ethan-1-ol is a chiral building block featuring a primary amine and hydroxyl group flanking a stereogenic center. This bench-stable, moisture-tolerant scaffold integrates readily into asymmetric synthesis, enabling direct access to bioactive intermediates in pharmaceutical development.

Application

(R)-2-Amino-2-(4-bromophenyl)ethan-1-ol serves as a key chiral building block for the synthesis of pharmaceutically relevant scaffolds. Its well-defined stereochemistry and compatible functional groups enable reliable incorporation into β-amino alcohol motifs, facilitating downstream transformations such as cyclization to heterocycles or derivatization via amine protection. The molecule exhibits good bench stability and is readily purified by standard chromatographic methods, supporting its use in both academic and industrial R&D workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 46.25
LogP 1.4412
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(R)-2-Amino-2-(4-bromophenyl)ethan-1-ol

CAS No. 354153-64-3

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