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Structure of 35387-92-9
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Methyl 4-iodo-3-methoxybenzoate features a strategically positioned iodine atom enabling direct cross-coupling reactions, while the ortho-methoxy group enhances solubility and stabilizes reaction intermediates. This bench-stable ester integrates readily into complex molecular architectures under standard conditions.
Methyl 4-iodo-3-methoxybenzoate serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient access to substituted aromatic scaffolds. The iodide group facilitates reliable Suzuki, Stille, and Negishi couplings, while the methoxy and ester functionalities offer orthogonal reactivity and stability under standard reaction conditions. This compound exhibits excellent bench stability and is readily purified by flash chromatography, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: