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CS-W001157 4
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2-Cyanoethylhydrazine

  • CAS No. 353-07-1

  • Cat. No. CS-W001874
  • Purity≥95%
  • MDL No.MFCD00043620

*For research and further manufacturing use only, not for direct human use.

2-Cyanoethylhydrazine|CS-W001874

Structure of 353-07-1

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General Information

  • CAS No. 353-07-1
  • Cat. No. CS-W001874
  • Purity ≥95%
  • MDL No. MFCD00043620
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₇N₃
  • Molecular Weight 85.11
  • Synonym(s) 3-Hydrazinylpropanenitrile
  • SMILES N#CCCNN

Description

2-Cyanoethylhydrazine serves as a key building block in the synthesis of nucleoside analogs and bioactive heterocycles. This hydrazine derivative features a cyanoethyl group that enhances reactivity while maintaining bench-stable handling characteristics under standard conditions.

Application

2-Cyanoethylhydrazine serves as a versatile building block in synthetic organic chemistry, enabling the construction of heterocyclic scaffolds through cyclization reactions. Its hydrazine functionality facilitates condensation with carbonyl compounds and activated esters, while the nitrile group offers compatibility with nucleophilic additions and polymerizable systems. The compound exhibits sufficient bench stability for routine handling and is valued for its role in synthesizing bioactive intermediates and functionalized polymers.

Synthesis

  • Route1
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      107-13-1
    • ~94%
    • In-stock
      2-Cyanoethylhydrazine|CS-W001874
      353-07-1

    References

    • Osei-Twum, Emmanuel Y.; McCallion, Doug; Nazran, Avtar S.; Panicucci, Rick; Risbood, Prabhakar A.; Warkentin, John Journal of Organic Chemistry, 1984 , vol. 49, # 2 p. 336 - 342
  • Route2
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      541-41-3
    • null|null
      107-13-1
    • ~%
    • In-stock
      2-Cyanoethylhydrazine|CS-W001874
      353-07-1

    References

    • US3987168 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2927
Class : 6.1 (8)
Packing Group : Ⅱ
Hazard Statements : H301-H314
Precautionary Statements : P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   61.84
  • LogP   -0.63662
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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