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Structure of 352530-29-1
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4-Ethynylpyridine hydrochloride offers a bench-stable, moisture-tolerant platform for copper-catalyzed click chemistry. The pyridyl nitrogen enhances solubility and coordination, while the terminal alkyne enables efficient coupling in diverse synthetic workflows. This reagent integrates seamlessly into modular synthesis strategies requiring robust, functionalized building blocks.
4-Ethynylpyridine hydrochloride serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to conjugated heteroaromatic systems. Its terminal alkyne functionality exhibits high reactivity in Sonogashira and CuAAC processes, while the pyridine nitrogen provides orthogonal coordination for catalysts or metal-directed functionalization. The hydrochloride salt enhances solubility and bench stability, facilitating handling and purification in synthetic workflows.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H228-H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P370+P378-P501
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Lot numbers can be found on the outside label of a product: