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CS-W001157 4
Total: USD 88.00

(E)-(3-Methylstyryl)boronic acid

  • CAS No. 352530-26-8

  • Cat. No. CS-0805722
  • Purity≥98%
  • MDL No.MFCD06202538

*For research and further manufacturing use only, not for direct human use.

(E)-(3-Methylstyryl)boronic acid|CS-0805722

Structure of 352530-26-8

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General Information

  • CAS No. 352530-26-8
  • Cat. No. CS-0805722
  • Purity ≥98%
  • MDL No. MFCD06202538
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BO₂
  • Molecular Weight 161.99
  • Synonym(s) None
  • SMILES B(/C=C/C1=CC=CC(=C1)C)(O)O

Description

(E)-3-Methylstyrylboronic acid features a stable boronate moiety conjugated to an (E)-configured styrenyl group, enabling efficient Suzuki-Miyaura coupling under mild conditions. This configuration enhances reproducibility in cross-coupling reactions, while the methyl substituent provides steric and electronic tuning for selective functionalization of complex molecular architectures.

Application

(E)-3-Methylstyrylboronic acid serves as a versatile boron building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of conjugated biaryl and styrenyl architectures. Its (E)-configured double bond ensures stereochemical fidelity in downstream transformations, while the boronic acid group offers excellent bench stability and compatibility with a range of functional groups. Ideal for synthesizing pharmaceutical intermediates and advanced materials, it facilitates straightforward purification and reliable coupling under mild reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.02022
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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