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Structure of 351534-36-6
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4-(3-Bromophenyl)piperidine is a bench-stable, moisture-tolerant building block featuring a brominated aromatic ring coupled to a piperidine heterocycle. This configuration enables direct functionalization in cross-coupling reactions and supports integration into bioactive molecules requiring electron-deficient aryl moieties.
4-(3-Bromophenyl)piperidine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling reactions. The brominated aryl group facilitates efficient Suzuki, Stille, and Negishi couplings, while the piperidine core provides a basic nitrogen for salt formation and pharmacokinetic modulation. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step synthesis workflows targeting CNS-active compounds and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P260-P280-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: