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CS-W001157 4
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1-(4-(Benzyloxy)phenyl)-2-bromopropan-1-one

  • CAS No. 35081-45-9

  • Cat. No. CS-0064620
  • Purity≥98%
  • MDL No.MFCD00017862

*For research and further manufacturing use only, not for direct human use.

1-(4-(Benzyloxy)phenyl)-2-bromopropan-1-one|CS-0064620

Structure of 35081-45-9

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General Information

  • CAS No. 35081-45-9
  • Cat. No. CS-0064620
  • Purity ≥98%
  • MDL No. MFCD00017862
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₅BrO₂
  • Molecular Weight 319.20
  • Synonym(s) 4'-Benzyloxy-2-bromopropiophenone
  • SMILES CC(Br)C(C1=CC=C(OCC2=CC=CC=C2)C=C1)=O

Description

Propargyl-PEG10-alcohol is a heterobifunctional PEG linker which enables Click Chemistry reactions with azide-bearing biomolecules; copper catalyst is needed. The hydrophilic PEG units increase aqueous solubility.

Synthesis

  • Route1

    References

    • ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2007/10217 A1, 2007 ; Location in patent: Page/Page column 32 ; WO 2007/010217 A1
  • Route2

    References

    • Bioorganic and Medicinal Chemistry, , vol. 14, # 19 p. 6581 - 6585
  • Route3

    References

    • Bioorganic and Medicinal Chemistry, , vol. 14, # 19 p. 6581 - 6585

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   4.2317
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   5

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