Methyl 4-amino-3,6-dichloropicolinate

Name: Methyl 4-amino-3,6-dichloropicolinate
Brand: ChemScene
Availability: InStock
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CAS No. 350601-39-7
Cat. No. CS-0136074
Purity≥97%
MDL No.MFCD28722246

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Methyl 4-amino-3,6-dichloropicolinate|CS-0136074

Structure of 350601-39-7

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Description

Methyl 4-amino-3,6-dichloropicolinate features a strategically positioned amino group flanked by two chlorine substituents on the picolinate core. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates, offering enhanced reactivity in cross-coupling and amidation processes under standard conditions.

Application

Methyl 4-amino-3,6-dichloropicolinate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds. The amino and ester functionalities offer orthogonal reactivity for downstream modifications, while the dichloro substitution pattern facilitates selective functionalization. Its bench-stable nature and compatibility with standard coupling and cyclization protocols make it well-suited for multi-step synthesis of bioactive heterocycles and API intermediates.

General Information

CAS No. 350601-39-7
Cat. No. CS-0136074
Purity ≥97%
MDL No. MFCD28722246
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆Cl₂N₂O₂
Molecular Weight 221.04
Synonym(s) Methyl 4-Amino-3,6-dichloropyridine-2-carboxylate
SMILES O=C(C1=NC(Cl)=CC(N)=C1Cl)OC

Computational Chemistry Data

TPSA 65.21
LogP 1.7572
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

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Methyl 4-amino-3,6-dichloropicolinate

CAS No. 350601-39-7

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