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CS-W001157 4
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2-Methyl-1H-imidazole-5-carbaldehyde

  • CAS No. 35034-22-1

  • Cat. No. CS-0186659
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methyl-1H-imidazole-5-carbaldehyde|CS-0186659

Structure of 35034-22-1

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General Information

  • CAS No. 35034-22-1
  • Cat. No. CS-0186659
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆N₂O
  • Molecular Weight 110.11
  • Synonym(s) 2-Methyl-1H-imidazole-4-carbaldehyde
  • SMILES CC1=NC=C(C=O)N1

Description

2-Methyl-1H-imidazole-5-carbaldehyde delivers a reactive aldehyde group flanked by an electron-rich imidazole scaffold, enabling direct incorporation into heterocyclic architectures. This bench-stable compound facilitates efficient coupling reactions in synthetic and medicinal chemistry workflows.

Application

2-Methyl-1H-imidazole-5-carbaldehyde serves as a versatile building block in heterocyclic synthesis, enabling efficient access to imidazole-based scaffolds through standard carbonyl transformations. Its aldehyde functionality facilitates reductive amination, Grignard additions, and coupling reactions with nucleophiles, while the electron-rich imidazole core exhibits favorable stability under mild reaction conditions. The methyl substituent enhances solubility and aids in purification, making it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   0.53062
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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