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CS-W001157 4
Total: USD 88.00

DL-Dithiothreitol

  • CAS No. 3483-12-3

  • Cat. No. CS-3035
  • Purity≥96%
  • MDL No.MFCD00004877

*For research and further manufacturing use only, not for direct human use.

DL-Dithiothreitol|CS-3035

Structure of 3483-12-3

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General Information

  • CAS No. 3483-12-3
  • Cat. No. CS-3035
  • Purity ≥96%
  • MDL No. MFCD00004877
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀O₂S₂
  • Molecular Weight 154.25
  • Synonym(s) DTT; rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol
  • SMILES SC[C@@H](O)[C@H](O)CS

Description

Reducing disulfide bonds via thiol-disulfide exchange, DL-Dithiothreitol (CAS 3483-12-3) forms a stable cyclic oxidized product upon redox cycling in biochemical assays.

Application

DL-Dithiothreitol (CAS 3483-12-3) drives mechanochemical disulfide reduction in protein-inspired mimics, revealing noncovalent sulfuroxygen chalcogen interactions in aqueous environments. It enables precise control of redox states. Researchers leverage this to decode disulfide dynamics for protein engineering and drug design. Its role extends into gut microbiome modeling, marine natural product synthesis, and forensic blood detection. Caution is warranted—its effects can extend beyond thiol-disulfide exchange.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3335
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H402
Precautionary Statements : P264-P270-P273-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.4322
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   3

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