Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(2-Pyrazinyl)-piperazine

  • CAS No. 34803-68-4

  • Cat. No. CS-0029554
  • Molecule weight164.21
  • Purity≥98%
  • MDL No.MFCD00040766

*For research and further manufacturing use only, not for direct human use.

1-(2-Pyrazinyl)-piperazine|CS-0029554

Structure of 34803-68-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 34803-68-4
  • Cat. No. CS-0029554
  • Purity ≥98%
  • MDL No. MFCD00040766
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₄
  • Molecular Weight 164.21
  • Synonym(s) 4-(2-Pyrazinyl)piperazine; N-(Pyrazin-2-yl)piperazine; 3,4,5,6-Tetrahydro-2H-[1,2']bipyrazine
  • SMILES C1(N2CCNCC2)=NC=CN=C1

Description

1-(2-Pyrazinyl)-piperazine features a pyrazinyl group directly fused to a piperazine core, creating a rigid, electron-deficient heterocyclic scaffold. This configuration enhances binding affinity in kinase inhibitors and other bioactive molecules. The compound serves as a key building block in medicinal chemistry, integrating readily into diverse pharmacophores via its nucleophilic nitrogen atoms.

Application

1-(2-Pyrazinyl)-piperazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard coupling reactions. Its pyrazine core provides enhanced metabolic stability and favorable physicochemical properties, while the piperazine moiety offers solubility and hydrogen-bonding capacity. The compound exhibits bench stability and facilitates straightforward functionalization, making it well-suited for lead optimization campaigns and API development workflows.

Synthesis

  • Route1
    • null|null
      110-85-0
    • In-stock
      Chloropyrazine|CS-W018537
      14508-49-7
    • ~70%
    • In-stock
      1-(2-Pyrazinyl)-piperazine|CS-0029554
      34803-68-4

    References

    • Komoto; Okada; Sato; Niino; Oka; Sakamoto Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 10 p. 1314 - 1320
  • Route2
    • null|null
      622386-07-6
    • ~%
    • In-stock
      1-(2-Pyrazinyl)-piperazine|CS-0029554
      34803-68-4

    References

    • Tetrahedron Letters, , vol. 47, # 15 p. 2549 - 2552

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   41.05
  • LogP   -0.1138
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-(2-Pyrazinyl)-piperazine sigma1-(2-Pyrazinyl)-piperazine manufacturer1-(2-Pyrazinyl)-piperazine price1-(2-Pyrazinyl)-piperazine structure1-(2-Pyrazinyl)-piperazine SDSbuy 1-(2-Pyrazinyl)-piperazine1-(2-Pyrazinyl)-piperazine supplier1-(2-Pyrazinyl)-piperazine uses1-(2-Pyrazinyl)-piperazine molecular weightprice of 1-(2-Pyrazinyl)-piperazine1-(2-Pyrazinyl)-piperazine chemical name formula of 1-(2-Pyrazinyl)-piperazine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label